Incidence and risk factors of micronutrient deficiency in patients with IBD and intestinal Behçet’s disease: folate, vitamin B12, 25-OH-vitamin D, and ferritin

Abstract Background Patients with inflammatory bowel disease (IBD) and intestinal Behçet’s (BD) are vulnerable to micronutrient deficiencies due diarrhea-related gastrointestinal loss poor dietary intake caused by disease-related anorexia. However, few studies have investigated the incidence risk factors for deficiency. Methods We retrospectively analyzed 205 patients IBD who underwent examination, including folate, vitamin B12, 25-OH-vitamin D, and/or ferritin level quantification, follow-up blood tests conducted 6 months later. Results Eighty (39.0%), were deficient in any of four micronutrients, classified as deficiency group, remaining 125 (61.0%) non-deficient group. Compared those non-deficiency group much younger, had more Crohn's (CD) patients, a history operation, significantly less 5-amino salicylic acid usage. Multivariate analysis revealed that CD operation significant independent associated Conclusions The was high (39.0%). Factors CD, younger ages found be higher risks Therefore, IBD, especially young undergone resection surgery, need attention paid micronutrition.